Cross-laminated timber (CLT) may require preservative treatment in markets with severe termite hazards. Given the size of CLT panels, conventional pressure treatment would not be feasible. We therefore assessed the treatability of CLT panels with an alternative low moisture uptake surface-applied penetrating process for applying termiticides. Hem-fir panels were selected for the initial tests on the grounds that western hemlock and amabilis fir are relatively treatable. Nine test panels were dip treated and stored for 7, 14, or 21 day activation periods. Borate retention ranged from 1.2 to 6.5 kg/m3 and penetration ranged from 3 to 9 mm. Longer activation periods did not result in improved penetration. Greater penetration would likely be needed to meet performance-based standards.