This new study aims to generate hygrothermal, particularly moisture-related performance data for light wood-frame walls meeting the R22 effective (RSI 3.85) requirement for buildings up to six storeys in the City of Vancouver. The overarching goal is to identify and develop durable exterior wood-frame walls to assist in the design and construction of energy efficient buildings across the country. Twelve test wall panels in six types of wall assemblies are assessed in this study. The wall panels, each measuring 4 ft. (1200 mm) wide and 8 ft. (2400 mm) tall, form portions of the exterior walls of a test hut located in the rear yard of FPInnovations’ Vancouver laboratory. This report, second in a series on this study, documents the performance of these wall assemblies based on the data collected over 19 months’ period from October 2018 to May 2020, covering two winter seasons and one summer.