The study investigated self-reported health effects among 223 tree planters at 13 sites in British Columbia and western Alberta, and measured personal exposure to fertilizer dust, heavy metals, and certain pesticides among a subgroup of 54. The study identified an association between chronic respiratory symptoms (cough, phlegm, and nasal symptoms), nosebleed, and skin irritation, and duration of work with fertilizers among tree planters. Overall, among the 54 individuals examined, measured exposures to heavy metals and dust were low. Pesticide exposure was also low, but residues found on seedlings and skin samples demonstrate a potential route of exposure. Opportunities exist for fairly straightforward improvements to hygiene conditions and dermal protection (i.e., glove) programs that would reduce the risk of exposure.